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ReNAgade Therapeutics unveiled new LNPs for delivering mRNA to extra-hepatic tissues: Patent analysis on its proprietary ionizable lipids

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…the ionizable lipids of the invention. Compounds 3 and 4 are also used as comparative ionizable lipids. Compound 4 was synthesized based on the work of Lokugamage et al. in 2019, while Compound 3 was synthesized based on the work of Zaho et al. in 2020. In detail, ionizable lipids,…

Acuitas Therapeutics filed a complaint against CureVac SE seeking inventorship: Pfizer & BioNtech potentially in the crosshairs

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…‘493 Patent Family, along with other patents. The case is still ongoing. Regarding Patent ‘493, according to BioNTech and Pfizer’ complaint, Comirnaty® vaccine does not comprise a “composition comprising a mRNA comprising . . . at least one pharmaceutically acceptable carrier, wherein the mRNA is complexed or associated with lipid…